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Christopher A. Shaw

Title:

Christopher A. Shaw
Professor, University of British Columbia

Organisation:

University of British Columbia

E-mail:

Website:

www.2010watch.com

Curriculum Vitae:

PRESENTATION

The hidden 4th pillar of olympism: Privatized profit, socialized debt - Play the Game 2009 (PP Pdf.)

POSITIONS
1. Dalhousie University. Research Associate. 1986-1988.
2. University of British Columbia. Assistant Professor. 1988-1993.
3. University of British Columbia. Associate Professor. 1993-2004.
4. University of British Columbia. Professor. 2005-present.

HONORS
1. Friends of the Hebrew University Scholarship. 1971-1973.
2. Hebrew University Graduate Scholarship. 1974-1976, 1978-1979.
3. Killam Postdoctoral Fellowship. 1979-1981.
4. NIH Postdoctoral Fellowship. 1981-1983.
5. BC Health Research Scholarship. 1988-1992.
6. Award for service. 39 Brigade Commander's Commendation. 1999.

PUBLICATIONS
Total Full Publications: 101
Total Abstracts: 142
Books: 5

Selected Journal Publications (last 5 years):
1.    Shaw, C.A. & Höglinger, G.U. Neurodegenerative diseases: neurotoxins as sufficient etiologic agents? J Neuromolecular Medicine. 10(1): 1-9, (2008).

2.    Tabata, R.C., Wilson, J.M.B., Van Kampen, J.M., Cashman, N., & Shaw, C.A. Dietary sterol glucosides are neurotoxic to motor neurons and induce an ALS-PDC phenotype. J Neuromolecular Medicine. 10(1): 24-39, (2008).

3.    Petrik, M.S., Wilson, J.M.B., Grant, S.C., Blackband, S.J., Tabata, R.C., Shan, X., Krieger, C., & Shaw, C.A. Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits. J Neuromolecular Medicine. 9(3): 216-229, (2007).

4.    Ly, P.T.T., Singh, S., & Shaw, C.A. Novel environmental toxins: steryl glucosides as a potential etiological factor for age-related neurodegenerative diseases. J Neurosci. Res. 85(2): 231-237, (2007).

5.    Cruz-Aguado, R., Winkler, D., & Shaw, C.A. Lack of behavioral and neuropathological effects of dietary b-methylaminoalanine (BMAA) in mice. Pharmacol, Biochem, Behav. 84: 294-299, (2006).

6.    Wilson, J.M.B. & Shaw, C.A. Commentary on Return of the cycad hypothesis – does the amyotrophic lateral sclerosis/parkinsonism dementia complex (ALS/PDC) of Guam have new implications for global health? Neuropathology and Applied Neurobiology 32: 341-343, (2006).

7.    Marler, T.E., Lee, V., & Shaw, C.A. Cycad toxins and neurological diseases in Guam: defining theoretical and experimental standards for correlation human disease with environmental toxins. Horticultural Science 33: 1598-1606 (2005).

8.    Schulz, J.D., Hawkes, E.L., & Shaw, C.A. Cycad toxins, helicobacter pylori and parkinsonism: cholesterol glucosides as the common denominator. Medical Hypothesis 40: 1598-1606, (2005).

9.    Schulz, J. D., Wilson, J. M. B., & Shaw, C. A.  A murine model of ALS-PDC with behavioral and neuropathological features of parkinsonism. Annals of the New York Academy of Sciences 991: 326-329, (2003).
    
10.    Shaw, C.A. & Wilson, J.M.B. Analysis of neurological disease in 4 dimensions: Insight from ALS-PDC epidemiology and animal models. Neurosci Biobehav Rev. Oct. 27(6): 493-505, (2003).

11.    Shaw, C.A. Do neurodegenerative cascades in Parkinson’s disease really reflect bottom-up processing? Behavioral and Brain Sciences, (2003).
    
12.    Khabazian, I., Bains, J.S., Williams, D.E., Cheung, J., Wilson, J.M.B., Pasqualotto, B.A., Pelech, S.L., Andersen, R.J., Wang, Y.-T., Liu, L., Nagai, A., Kim, S.U., Craig, U.-K., & Shaw, C.A. Isolation of various forms of sterol b-d-glucoside from the seed of Cycas circinalis: neurotoxicity and implications for ALS-PDC. J. Neurochem. 82: 1-13, (2002).

C. Research Support
Ongoing Research Support

National Institute of Neurological Disorders and Stroke (R01)          
Time-lines of neural degeneration in ALS-PDC mouse model
CA Shaw(PI)            08/06 – 01/11

ALSA US/ALS Society of Canada
        
Roles of sterol glucoside neurotoxicity in ALS-PDC
CA Shaw (PI)            08/06 – 07/09

Scottish Rite Charitable Foundation of Canada
                               
Neurobiological basis of cycad toxicity in a mouse model of ALS-PDC
CA Shaw (PI)            04/07 – 04/09

National Institute of Neurological Disorders and Stroke (R03)
               
Neurotoxicity of sterol glucosides: role in ALS-PDC
CA Shaw (PI)            04/07 – 02/09

The Pacific Alzheimer’s Research Foundation                               
Role of progranulin in brain function and neuroprotection
CA Shaw (PI)            04/07 – 03/10