PRESENTATION
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POSITIONS 1. Dalhousie University. Research Associate. 1986-1988. 2. University of British Columbia. Assistant Professor. 1988-1993. 3. University of British Columbia. Associate Professor. 1993-2004. 4. University of British Columbia. Professor. 2005-present.
HONORS 1. Friends of the Hebrew University Scholarship. 1971-1973. 2. Hebrew University Graduate Scholarship. 1974-1976, 1978-1979. 3. Killam Postdoctoral Fellowship. 1979-1981. 4. NIH Postdoctoral Fellowship. 1981-1983. 5. BC Health Research Scholarship. 1988-1992. 6. Award for service. 39 Brigade Commander's Commendation. 1999.
PUBLICATIONS Total Full Publications: 101 Total Abstracts: 142 Books: 5
Selected Journal Publications (last 5 years): 1. Shaw, C.A. & Höglinger, G.U. Neurodegenerative diseases: neurotoxins as sufficient etiologic agents? J Neuromolecular Medicine. 10(1): 1-9, (2008).
2. Tabata, R.C., Wilson, J.M.B., Van Kampen, J.M., Cashman, N., & Shaw, C.A. Dietary sterol glucosides are neurotoxic to motor neurons and induce an ALS-PDC phenotype. J Neuromolecular Medicine. 10(1): 24-39, (2008).
3. Petrik, M.S., Wilson, J.M.B., Grant, S.C., Blackband, S.J., Tabata, R.C., Shan, X., Krieger, C., & Shaw, C.A. Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits. J Neuromolecular Medicine. 9(3): 216-229, (2007).
4. Ly, P.T.T., Singh, S., & Shaw, C.A. Novel environmental toxins: steryl glucosides as a potential etiological factor for age-related neurodegenerative diseases. J Neurosci. Res. 85(2): 231-237, (2007).
5. Cruz-Aguado, R., Winkler, D., & Shaw, C.A. Lack of behavioral and neuropathological effects of dietary b-methylaminoalanine (BMAA) in mice. Pharmacol, Biochem, Behav. 84: 294-299, (2006).
6. Wilson, J.M.B. & Shaw, C.A. Commentary on Return of the cycad hypothesis – does the amyotrophic lateral sclerosis/parkinsonism dementia complex (ALS/PDC) of Guam have new implications for global health? Neuropathology and Applied Neurobiology 32: 341-343, (2006).
7. Marler, T.E., Lee, V., & Shaw, C.A. Cycad toxins and neurological diseases in Guam: defining theoretical and experimental standards for correlation human disease with environmental toxins. Horticultural Science 33: 1598-1606 (2005).
8. Schulz, J.D., Hawkes, E.L., & Shaw, C.A. Cycad toxins, helicobacter pylori and parkinsonism: cholesterol glucosides as the common denominator. Medical Hypothesis 40: 1598-1606, (2005).
9. Schulz, J. D., Wilson, J. M. B., & Shaw, C. A. A murine model of ALS-PDC with behavioral and neuropathological features of parkinsonism. Annals of the New York Academy of Sciences 991: 326-329, (2003). 10. Shaw, C.A. & Wilson, J.M.B. Analysis of neurological disease in 4 dimensions: Insight from ALS-PDC epidemiology and animal models. Neurosci Biobehav Rev. Oct. 27(6): 493-505, (2003).
11. Shaw, C.A. Do neurodegenerative cascades in Parkinson’s disease really reflect bottom-up processing? Behavioral and Brain Sciences, (2003). 12. Khabazian, I., Bains, J.S., Williams, D.E., Cheung, J., Wilson, J.M.B., Pasqualotto, B.A., Pelech, S.L., Andersen, R.J., Wang, Y.-T., Liu, L., Nagai, A., Kim, S.U., Craig, U.-K., & Shaw, C.A. Isolation of various forms of sterol b-d-glucoside from the seed of Cycas circinalis: neurotoxicity and implications for ALS-PDC. J. Neurochem. 82: 1-13, (2002).
C. Research Support Ongoing Research Support
National Institute of Neurological Disorders and Stroke (R01) Time-lines of neural degeneration in ALS-PDC mouse model CA Shaw(PI) 08/06 – 01/11
ALSA US/ALS Society of Canada Roles of sterol glucoside neurotoxicity in ALS-PDC CA Shaw (PI) 08/06 – 07/09
Scottish Rite Charitable Foundation of Canada Neurobiological basis of cycad toxicity in a mouse model of ALS-PDC CA Shaw (PI) 04/07 – 04/09
National Institute of Neurological Disorders and Stroke (R03) Neurotoxicity of sterol glucosides: role in ALS-PDC CA Shaw (PI) 04/07 – 02/09
The Pacific Alzheimer’s Research Foundation Role of progranulin in brain function and neuroprotection CA Shaw (PI) 04/07 – 03/10 |